New Coronavirus Nucleic Acid Detection Kit
The COVID-19 IgG/IgM Rapid Test Device is an in vitro immunoassay for the direct and qualitative detection of anti-SARS-CoV-2 IgM and anti-SARS-CoV-2 IgG in human whole blood, serum, or plasma as an aid in the diagnosis of COVID-19.The test is for professional use only
- high sensitivity: 100 times higher sensitivity than traditional NanoDrop;
- wide linear range: wider linear range than traditional NanoDrop;
- good specificity: quantification of DNA or RNA can be achieved respectively;
- simple operation: mix-and-read format;
- wide applicability: can use fluorescein marker, also compatible with fluorescein devices such as Qubit®, Quantus™.
Coronaviruses are a large family of viruses that are common in many different species of animals, including camels, cattle, cats, and bats. The two highly pathogenic viruses, SARS-CoV and MERS-CoV, cause severe respiratory syndrome in humans, and the other four human coronaviruses (HCoV-NL63, HCoV-229E, HCoV-OC43 and HKU1) induce only mild upper respiratory diseases in immunocompetent hosts, although some of them can cause severe infections in infants, young children and elderly individuals1,2,3.
COVID-19 is the disease associated with SARS-CoV-2, which was identified in China at the end of 2019. Coronaviruses cause respiratory and intestinal infections in animals and humans. The virus is transmitted mainly via respiratory droplets that people sneeze, cough, or exhale. The incubation period for COVID-19 is currently estimated at between two and 14 days. Common symptoms of COVID-19 infection include fever, cough and respiratory symptoms such as shortness of breath and breathing difficulties. More serious cases develop severe pneumonia, acute respiratory distress syndrome, sepsis and septic shock that can lead to the death of the patient. People with existing chronic conditions seem to be more vulnerable to severe illness.
Detection of IgM indicates recent infection and can be used for early diagnosis of infection. IgG antibodies gradually appear and increase in the late stage of infection, and the COVID-19 IgG/IgM Rapid Test Device is a simple lateral flow immunoassay for the direct detection of anti-SARS-CoV-2 IgG/IgM antibody. It will provide a presumptive diagnosis of COVID-19.
The product can add internal standard in the detection reagent to prevent false negative test results. At the same time, the positive quality control product and internal standard of the kit are simulated RNA virus particles, which are closer to the virus structure and contain protein package. They are extracted together with the samples to better monitor the whole experimental process and ensure the reliability of the test results. In addition, the reagent of this product can be equipped with automatic nucleic acid extraction instrument and fluorescence quantitative PCR instrument to realize detection automation, improve detection speed and protect the safety of front-line workers.